Chicago Center for Anti-Aging vitamin herbal supplements

Buy Cheap All-Natural Chicago Seasonal Discomfort Support Anti-Aging Herbal Supplements Vitamins

Why pick our Natural Seasonal Discomfort Support Herbal Supplement?Natural-Seasonal-Discomfort-Support

There are many options available today when choosing vitamins and anti-aging supplements. This means that you have to be careful as a consumer and make sure you choose a reliable manufacturer who only uses the highest quality ingredients. The Chicago Center For Anti-Aging has partnered with one of the most reputable manufacturers which helps ensure the quality of our private line of vitamins and anti-aging supplements. Quality is what should be the most important attribute you should look for to help make your decision, not cost. Look for quality you can trust.

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Dose Form
Natural D-Hist, Product #524: Two-piece Vegetable Capsule
D-Hist Jr., Product #855: Chewable Tablet

Other Ingredients
Natural D-Hist, Product #524: Natural Vegetable Capsules. This product may contain one or more of the following: Calcium Silicate, Magnesium Stearate, Microcrystalline Cellulose and Silicon Dioxide.
D-Hist Jr., Product #855: Natural Cane Sugar, Lemon-Lime Flavoring, Vanilla Flavoring, Xylitol, Magnesium Stearate, Stevia Leaf Extract and Cabosil. This product may contain Croscarmellose Sodium.

Product Rationale
Natural D-Hist is a synergistic formula having mast cell stabilizing activity combined with agents that inhibit the mediation of allergies. Natural D-Hist can be used for seasonal support.

Research Findings
Among the flavonoids, quercetin is one of the most biologically active. It is widely distributed in plants including Oak trees (Quercus spp.), onions (Allium cepa) and tea (Camellia sinensis).
• Quercetin inhibits histamine release from antigen-induced (IgE-induced) mast cells and basophils1,2 –related to its ability to block Calcium influx by inhibiting calmodulin activity3.
• Quercetin has in vitro mast cell stabilizing activity greater than sodium cromolyn4 (synthetic pharmaceutical mast cell stabilizer).
• Quercetin inhibits lipoxygenase (LOX), platelet aggregation, and mast cell and basophil degranulation. Quercetin is amast cell stabilizer, keeping histamine and other preformed mediators from being released5.
Stinging Nettles:
• Randomized, Double-Blind Study with Placebo: 98 allergy sufferers given placebo or Stinging Nettles- Urtica dioica was rated higher than placebo by patients6.
• Positive Commission E monograph for use as supportive therapy for rheumatic ailments.
• Potential Mechanisms include:
1. Inhibition of inflammatory enzymes 5-lipoxygenase and cyclooxygenase7.
2. Inhibition of the pro-inflammatory transcription factor NF-kappaB8.
Bromelain is the term used to describe a group of enzymes derived from the stem and fruit of the pineapple plant (Ananascomosus). As a plant enzyme, bromelain has many advantages and uses as a supplement ingredient. Bromelain is considered an anti-inflammatory agent due to its ability to inhibit arachidonic acid formation by Phospholipase A9. An activity related to its enzymatic degradation of the proinflammatory bradykinin molecule10. Bromelain is believed to increase absorption of other molecules11- including bioflavonoids like quercetin12.
N- Acetyl Cysteine (NAC):
NAC is used primarily as a precursor to the important antioxidant glutathione13; and is also a mucolytic agent- able to breakdown the viscosity of mucus within the lungs- a common cause of allergy related asthma.

Natural D-Hist, Product #524:
Loading Dose: 2-3 capsules three times per day for 7-10 days
Maintenance Dose: 1 or more capsules per day
Acute Flair-up: 2-3 capsules as needed
D-Hist Jr., Product #855:
1-2 tablets two times per day

Contraindications, Adverse or Other Reactions
Mild stomach upset or allergic reaction may occur with any herbal product, move dose closer to meals or cease product if
symptoms persist. Patients should ingest a single capsule before ingesting large doses to ensure no reaction will occur with higher
Patients on blood-thinning drugs such as warfarin (coumadin) or heparin should use caution as bromelain may amplify their effects.

How can I purchase this Natural Seasonal Discomfort Support Vitamin?

Even if you are not a member of the Chicago Center For Anti-Aging, you can still purchase any of our private and unique anti-aging supplements and vitamins. You can drop by our office anytime and pick up any of our products. We are conveniently open 7 days a week from 8am-8pm.

If you want to place an order for delivery, call us at 847.696.9900 and you can order anything you want. Mention our website and you will receive 2 day USPS shipping for any sized order for only $5!

Finally, you can also order online at, which is the only place online allowed to sell our products...

1. Kimata M, Shichijo M, Miura T, Serizawa I, Inagaki N, Nagai H.. Effects of luteolin, quercetin and baicalein on immunoglobulin E-mediated mediator release from human cultured
mast cells.. Clin Exp Allergy 2000 Apr;30(4):501-8.
2. Middleton, E, Drzewiecki G, Krishnarao D. Quercetin: An inhibitor of antigen-induced human basophil histamine release. J Immunology 1981 127:(2):546-550
3. Nishino H, et al. Quercetin interacts with calmodulin, a calcium regulatory protein. Experientia 1984 40: 184-185
4. Otsuka H, Inaba M, Fujikura T, Kunitomo M. Histochemical and functional characteristics of metachromatic cells in the nasal epithelium in allergic rhinitis: studies of nasal scrapings and their dispersed cells. J Allergy Clin Immunol 1995 ;96(4):528-36
5. Kim HP, Mani I, Iversen L, Ziboh VA. Effects of naturally-occurring flavonoids and biflavonoids on epidermal cyclooxygenase and lipoxygenase from guinea-pigs. Prostaglandins Leukot Essent Fatty Acids 1998; 58(1):17-24
6. Guilliams T. Allergies: The Natural Approach. The Standard. 1998;1(2):1-8.
7. Obertreis, B. Anti-inflammatory effect of Urtica dioica folia extract in comparison to caffeic malic acid. Arzneimittelforschung, 1996; 46(1): 52-56.
8. Riehemann K, Behnke B, Schulze-Osthoff K. Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-kappaB. FEBS Lett 1999; 442(1): 89-94
9. Vellini M et al. Possible involvement of eicosanoids in the pharmacological action of bromelain. Arzneimittelforschung 1986; 36(1): 110-2
10. Kumakura S, Yamashita M, Tsurufuji S. Effect of bromelain on kaolin-induced inflammation in rats. Eur. J. Pharmacol 1988; 150(3): 295-301
11. Bock U et al. Transport of proteolytic enzymes across Caco-2 cell monolayers. Pharm Res 1998; 15(9): 1393-1400
12. Shoskes DA, Zeitlin SI, Shahed A, Rajfer J. Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial. Urology 1999; 54(6): 960-3
13. Yim, C.Y. Use of N-acetyl cysteine to increase intracellular glutathione during the induction of antitumor responses by IL-2. J. Immul. 1994; 152: 5796-5805.
14. Ziment, I. Acetyl cysteine: a drug that is much more than a mucokinetic. Biomed Pharmacother. 1988; 42(8): 513-519.
15. Millar, A.B. Effect of oral N-Acetyl Cysteine on mucus clearing. Br J Dis Chest 1985; 79: 262-266.

** Information for health care professionals only.

** These statements have not been evaluated by the FDA.  This product is not intended to treat, diagnose, prevent, or cure any disease.  Consult a physician before taking.  Should you experience any serious physical side effects from taking these nutritional supplements, discontinue and call your doctor immediately.